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KMID : 1123920100240010085
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Korean Journal of Oriental Physiology and Pathology
2010 Volume.24 No. 1 p.85 ~ p.90
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Effect of Ginseng-Berry Extract on the Improvement of Blood Microcirculation and Skin Brightness
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Kim Jeong-Kee
Kim Byung-Soo
Park Chan-Woong
Seo Dae-Bang
Yoo Ho-Rhyong
Lee Sang-Jun
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Abstract
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Several studies have demonstrated that ginseng-berry extract has several beneficial properties, including anti-inflammatory, antioxidant, and vasodilation properties. Ginseng-berry extract has also been shown to have the great potential against skin aging. Its beneficial mechanism against skin aging, however, has not been examined in detail. Also, the effects of ginseng-berry extract on microcirculation and skin cellular responses have not been investigated. Inhibition of skin microcirculation is the primary cause of many adverse biological effects, which is responsible for the skin aging and darkening. We investigated the beneficial effects of ginseng-berry extract on blood circulation, transcutaneous oxygen pressure in vivo model and also on skin microcirculation, cellular response and skin brightening effect in clinical trial. We found that oral administration of ginseng-berry extract markedly increased blood flow rate and transcutaneous pressure, but decreased transcutaneous pressure. Also, it improved skin tone on cheeks, as is skin brighteness. These results suggest that ginseng-berry extract is a potent candidate for the treatment of skin aging and brightening by improving skin microcirculation.
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KEYWORD
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ginseng-berry, microcirculaation, transcutaneous gas pressure, brighteness
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